A2 Adrenoceptor Agonists
Mostrando 1-12 de 53 artigos, teses e dissertações.
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1. Role of adenylyl cyclase in reduced β-adrenoceptor-mediated vasorelaxation during maturation
Beta-adrenergic receptor (βAR)-dependent blood vessel relaxation is impaired in older animals and G protein activation has been suggested as the causative mechanism. Here, we investigated the role of βAR subtypes (β1AR, β2AR, and β3AR) and cAMP in maturation-dependent vasorelaxation impairment. Aortic rings from 15 Sprague-Dawley male rats (3 or 9 weeks
Braz J Med Biol Res. Publicado em: 04/07/2016
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2. ANESTESIA EPIDURAL COM ALFA 2-AGONISTAS E LIDOCAÍNA PARA REALIZAÇÃO DE OVARIOSSALPINGOHISTERECTOMIA EM CADELAS / EPIDURAL ANESTHESIA WITH ALPHA 2-AGONISTS AND LIDOCAINE FOR OVARYHYSTERECTOMY IN BITCHES
Objetivou-se determinar a viabilidade e efeitos cardiorrespiratórios da associação entre diferentes agonistas a2-adrenérgicos e lidocaína via epidural para realização de ovariossalpingohisterectomia (OSH) em cadelas. Foram castradas 42 cadelas, as quais eram mantidas sob anestesia epidural lombo-sacral com lidocaína 1% com vasoconstrictor (CON) ou em
Publicado em: 2010
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3. Investigations into the presence of functional ß1, ß2 and ß3-adrenoceptors in urothelium and detrusor of human bladder
Purpose: We investigated the presence of functional ß1, ß2 and ß3-adrenoceptor in urothelium and detrusor muscle of human bladder through in vitro pharmacology of selective ß3 adrenoceptor agonist solabegron. Materials and Methods: Expression of these adrenoceptors in surgically separated human urothelium and detrusor muscle were investigated using RT-PC
International braz j urol. Publicado em: 2009-02
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4. Resposta inotropica a catecolaminas em miocitos ventriculares isolados de ratos submetidos a choque nas patas / Inotropic esponsiveness to catecholamines in ventricular myocytes isolated from footshock-stressed rats
Supersensitivity to isoproterenol (ISO) chronotropic effect has been described in right atria from footshock-stressed rats, but information on inotropic responsiveness, particularly of the ventricles, is scarce. The goal of this study was to analyze the inotropic and pro-arrhythmic effect of catecholamines on left ventricular myocytes from footshockstressed
Publicado em: 2007
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5. Effect of salbutamol on innervated and denervated rat soleus muscle
The objective of the present investigation was to perform a 14-day time-course study of treatment with salbutamol, a ß2 adrenoceptor agonist, on rat soleus muscle in order to assess fiber type selectivity in the hypertrophic response and fiber type composition. Male Wistar rats were divided into four groups: control (N = 10), treated with salbutamol (N = 30
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-12
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6. Receptores de glicocorticoides e subtipos de adrenoceptores beta em atrio direito de ratos submetidos a estresse
Right atria of male or female rats sacrificed at diestrus and submitted to foot shock stress show supersensitivity to non-selective and selective Bz-adrenoceptor agonists. This supersensitivity was due to increased Bz-adrenoceptor protein level expression. This tissue also showed subsensitivity to non selective Bl-adrenoceptor agonist, but no changes in BI a
Publicado em: 2002
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7. Sensibilidade a agonistas [beta]-adrenergicos em atrio esquerdo isolado de ratos submetidos a estresse
Following foot shock stress white adipocytes and right atria from male and right atria from female rats sacrificed at diestrous, are supersensitive to the chronotropic effect of isoprenaline. Right atria from female rats are also subsensitive to noradrenaline. In the present study, we investigated whether the inotropic response to B-adrenergic agonists was a
Publicado em: 2002
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8. Metabolic markers following beta-adrenoceptor agonist infusion in footshock-stressed rats
Stress hormones can alter metabolic functions in adipose tissue and liver, as well as the sensitivity of rat white adipocytes and rat atrial responses to ß-adrenergic agonists. In this study, we examined the effects of three daily footshock stress sessions on the plasma corticosterone, glucose, glycerol and triacylglycerol levels of fed, conscious male rats
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-09
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9. Effects of selective alpha 1-, alpha 2-, beta 1-and beta 2-adrenoceptor stimulation on potentials and contractions in the rabbit heart.
Selective adrenoceptor agonists and antagonists have been used to analyse the effects of stimulation of individual types of adrenoceptor in various parts of the rabbit heart. The selective alpha 1- and alpha 2-adrenoceptor agonists used were St 587 and BHT 933 respectively, and the antagonists were prazosin (alpha 1) and WY 25309 (alpha 2). The selective bet
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10. The action of beta-adrenoceptor agonists on acid secretion by the rat isolated stomach.
1. The action of beta-adrenoceptor agonists on acid secretion by an immature rat isolated stomach preparation has been studied. 2. Isoprenaline, salbutamol, salmefamol, adrenaline and noradrenaline all stimulated acid output over a concentration range of 2 X 10(-7) M--10(-5) M. 3. These responses were antagonized by propranolol (2 X 10(-5) M), pindolol and t
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11. Functional beta3-adrenoceptor in the human heart.
Beta3-adrenoceptors are involved in metabolism, gut relaxation, and vascular vasodilation. However, their existence and role in the human heart have not been documented. We investigated the effects of several beta-adrenoceptor agonists and antagonists on the mechanical properties of ventricular endomyocardial biopsies. In the presence of nadolol, a beta1- an
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12. Stimulation of anion secretion by beta-adrenoceptors in the mouse endometrial epithelium.
1. Regulation of anion secretion by adrenoceptors in primary culture of mouse endometrial epithelium was investigated using the short circuit current (ISC) technique. 2. Adrenaline stimulated a sustained increase in the ISC in a concentration-dependent manner. The adrenaline-induced ISC could be inhibited by pretreatment with diphenylamine 2,2'-dicarboxylic