Accessory Chromosome
Mostrando 1-12 de 50 artigos, teses e dissertações.
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1. Meiotic and mitotic behaviour of B chromosomes of ryegrass.
2010
Ciência Rural. Publicado em: 2011
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2. Identification of a yeast artificial chromosome clone encoding an accessory factor for the human interferon gamma receptor: evidence for multiple accessory factors.
Human chromosomes 6 and 21 are both necessary to confer sensitivity to human interferon gamma (Hu-IFN-gamma), as measured by the induction of human HLA class I antigen. Human chromosome 6 encodes the receptor for Hu-IFN-gamma, and human chromosome 21 encodes accessory factors for generating biological activity through the Hu-IFN-gamma receptor. A small regio
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3. The human gamma interferon receptor accessory factor encoded by chromosome 21 transduces the signal for the induction of 2',5'-oligoadenylate-synthetase, resistance to virus cytopathic effect, and major histocompatibility complex class I antigens.
Mouse fibroblasts, and human-mouse hybrid fibroblasts carrying only human chromosome 21, were transfected with cDNA encoding full-length human gamma interferon (IFN-gamma) receptor or chimeric IFN-gamma receptor (extracellular domain of the human receptor; transmembrane and intracellular domains of mouse origin). These transfected mouse cells were sensitive
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4. Efficient Male and Female Germline Transmission of a Human Chromosomal Vector in Mice
A small accessory chromosome that was mitotically stable in human fibroblasts was transferred into the hprt− hamster cell line CH and developed as a human chromosomal vector (HCV) by the introduction of a selectable marker and the 3′ end of an HPRT minigene preceded by a loxP sequence. This HCV is stably maintained in the hamster cell line. It consists m
Cold Spring Harbor Laboratory Press.
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5. De novo interstitial deletion in the long arm of chromosome 9: a new chromosome syndrome.
An infant with an interstitial deletion 46,XY, del(9)(pter leads to q22::q32 leads to qter) is described. Clinical features included abnormal craniofacies with hypotelorism, narrow palpebral fissures, sclerocornea, deep vertical groove, and supraorbital ridge hypoplasia. There was unilateral preaxial polydactyly and toe syndactyly. Generalised hirsutism was
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6. Chromosome End Maintenance by Telomerase*
Telomeres, protein-DNA complexes at the ends of eukaryotic linear chromosomes, are essential for genome stability. The accumulation of chromosomal abnormalities in the absence of proper telomere function is implicated in human aging and cancer. Repetitive telomeric sequences are maintained by telomerase, a ribonucleoprotein complex containing a reverse trans
American Society for Biochemistry and Molecular Biology.
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7. Accessory cholera enterotoxin (Ace), the third toxin of a Vibrio cholerae virulence cassette.
Vibrio cholerae causes the potentially lethal disease cholera through the elaboration of the intestinal secretogen cholera toxin. A second toxin of V. cholerae, Zot, decreases intestinal tissue resistance by modifying intercellular tight junctions. In this report, a third toxin of V. cholerae, Ace (accessory cholera enterotoxin), is described. Ace increases
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8. Type-Specific Contributions to Chromosome Size Differences in Escherichia coli
The Escherichia coli genome varies in size from 4.5 to 5.5 Mb. It is unclear whether this variation may be distributed finely throughout the genome or is concentrated at just a few chromosomal loci or on plasmids. Further, the functional correlates of size variation in different genome copies are largely unexplored. We carried out comparative macrorestrictio
American Society for Microbiology.
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9. Molecular cytogenetic characterisation of a small ring X chromosome in a Turner patient and in a male patient with congenital abnormalities: role of X inactivation.
The association of small accessory marker chromosomes in man with specific abnormalities has been difficult to define owing to variations in the chromosome origin and the size of the markers. In a patient with typical Turner phenotype and a 45,X/46,X, + mar karyotype the marker was shown to be a small portion of the long arm of the X chromosome which include
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10. Regulation of exoprotein expression in Staphylococcus aureus by a locus (sar) distinct from agr.
A single insertion of transposon Tn917LTV1 into the chromosome of a Staphylococcus aureus clinical isolate, strain DB, resulted in a pleiotropic effect on the expression of a number of extracellular and cell-wall-associated proteins. Detailed comparison of phenotypes associated with the mutant, 11D2, and the parent, DB, indicated that the chromosomal locus i
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11. The NDUFA1 gene product (MWFE protein) is essential for activity of complex I in mammalian mitochondria
The MWFE polypeptide of mammalian complex I (the proton-translocating NADH-quinone oxidoreductase) is 70 amino acids long, and it is predicted to be a membrane protein. The NDUFA1 gene encoding the MWFE polypeptide is located on the X chromosome. This polypeptide is 1 of approximately 28 “accessory proteins” identified in complex I, which is composed of
The National Academy of Sciences.
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12. Protein affinity chromatography with purified yeast DNA polymerase alpha detects proteins that bind to DNA polymerase.
We have overexpressed the POL1 gene of the yeast Saccharomyces cerevisiae and purified the resulting DNA polymerase alpha polypeptide in an apparently intact form. We attached the purified DNA polymerase covalently to an agarose matrix and used this matrix to chromatograph extracts prepared from yeast cells. At least six proteins bound to the yeast DNA polym