Acetylenes
Mostrando 1-8 de 8 artigos, teses e dissertações.
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1. ENAMINONAS: SÍNTESE E APLICAÇÃO EM REAÇÕES DE CICLOISOMERIZAÇÃO E DE ACOPLAMENTO / Enaminones: Synthesis and application in cycloisomerization reactions and coupling
Neste trabalho é descrita a síntese de uma série de vinte 4-[alquil(aril) (2-propinilamino)]-3-alquen-2-onas [R2C(O)CH=C(R1)N(R)(CH2CCH), onde R2= CF3,CCl3, CO2Et; R1= Me, Et, Pr e R= Pr, Ph, Bn, 4-MeC6H4] obtidas com rendimentos entre 70-95%, através de uma reação de adição-1,4 seguida de substituição, entre aminas propargílicas [NH(R)(CH2CCH), o
Publicado em: 2009
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2. Sintese e reações de alguns compostos ciclicos de tres membros com complexos de metais de transição
With the aim of studying the reactivity of some cyclopropane derivatives with respect to certain transition metal complexes of the d group, the a-chlorine-a-(cyclopropiliden)-methyl acetates 1a and 1b, the alquinilcyclopropanes 2a-i and the 3-cyclopropil-2H-azirine 3a were synthesized. Reactions of these cyclopropanes with organometalic complexes of the nick
Publicado em: 2004
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3. Sintese estereosseletiva do tamoxifeno, um agente antiestrogenico na terapia do cancer de mama
Tamoxifen is a non-steroidal antiestrogenic agent largely used in breast cancer therapy, particularly, in pacients with high risk to develop the disease after removal of the primary tumor. The structure of tamoxifen is relatively simple and could be reduced for synthetic purpose to a tetrasubstituted olefin. The (Z)-isomer (1) has antiestrogenic activity, wh
Publicado em: 2002
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4. Infrared spectroscopic investigations on the metallation of terminal alkynes by Zn(OTf)2
An IR study of terminal acetylenes and Zn(OTf)2 in the presence of amine bases provides evidence that is consistent with the generation of Zn-acetylides.
National Academy of Sciences.
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5. Growth Promotion in Pea Stem Sections. III. By Alkyl Nitriles, Alkyl Acetylenes and Insect Juvenile Hormones 1
C14, C15, and C16 alkyl nitriles, and C16 and C18 alkyl acetylenes at 10 to 105 micromolar concentrations promote the growth of stem sections from red-light-exposed seedlings of dwarf peas (Pisum sativum L. cv. Progress No. 9). Similar results were obtained with substances active as insect juvenile hormones, namely farnesol, the racemic ethyl ester of 1 of t
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6. [omega]-Hydroxylation of Oleic Acid in Vicia sativa Microsomes (Inhibition by Substrate Analogs and Inactivation by Terminal Acetylenes).
Oleic acid (18:1) is hydroxylated exclusively on the terminal methyl by a microsomal cytochrome P-450-dependent system ([omega]-OAH) from clofibrate-induced Vicia sativa L. (var minor) seedlings (F. Pinot, J.-P. Salaun, H. Bosch, A. Lesot, C. Mioskowski, F. Durst [1992] Biochem Biophys Res Commun 184: 183-193). This reaction was inactivated by two terminal a
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7. Estimation of nitrogenase activity in the presence of ethylene biosynthesis by use of deuterated acetylene as a substrate.
Nitrogenase reduces deuterated acetylene primarily to cis dideuterated ethylene. This can be distinguished from undeuterated ethylene by the use of Fourier transform infrared spectroscopy. Characteristic bands in the region from 800 to 3,500 cm-1 can be used to identify and quantitate levels of these products. This technique is applicable to field studies of
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8. Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation
The 1,3-dipolar cycloaddition reaction between unactivated azides and acetylenes proceeds exceedingly slowly at room temperature. However, considerable rate acceleration is observed when this reaction occurs inside the active center gorge of acetylcholinesterase (AChE) between certain azide and acetylene reactants, attached via methylene chains to specific i
National Academy of Sciences.