Adjuvants Immunologic
Mostrando 1-5 de 5 artigos, teses e dissertações.
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1. Clonagem, expressão e avaliação da imunogenicidade e do potencial adjuvante induzidos pela proteína "heat-shock" Cpn60 da Bordetella pertussis. / Molecular cloning, expression and evaluation of immunogenicity and adjuvant potential induced from the heat-shock protein Cpn60 from Bordetella pertussis.
The Cpn60 protein is a member of a group of higly conserved proteins linked to essencial cell functions. The Cpn60 was cloned, expressed and its immune response has been evaluated. BALB\c mice were immunized with 5 or 10 µg of the recombinant protein (Cpn60r) alone or mixed with DPT vaccine without aluminum hidroxyde (NADPT). The DPT vaccine from Instituto
Publicado em: 2010
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2. Imunologic response (Th2/Th1) in mice BALB/c previously sensitized with ovalbumin and injected with microspheres of PLGA encapsulated with OVA / Modulação da resposta imunologica (Th2/Th1) em camundongos BALB/c previamente sensibilizados com ovalbumina e injetados com microesferas de PLGA encapsuladas com OVA
A imunoterapia é a estratégia empregada no tratamento das doenças alérgicas que, quando bem indicada, é considerada eficaz com redução dos sintomas. Apesar disso, uma das desvantagens é a possibilidade de surgirem reações sistêmicas adversas durante o tratamento. Dentro do contexto de inovação tecnológica, o surgimento da nanotecnologia oferece
Publicado em: 2006
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3. Acitretin therapy for chemoprophylaxis of skin cancer in renal transplant recipients: clinical, histological and immunohistochemical evaluation. / Uso de acitretina para prevenção e tratamento de câncer de pele em transplantados renais: avaliação clínica, histológica e imuno-histoquímica
Renal transplant recipients have an increased incidence of actinic keratosis and skin cancer. In order to examine the chemoprophylatic effects of low-dose acitretin on skin cancer development we submitted 13 renal transplanted patients to acitretin therapy (20 mg/day) for 12 month. The patients were assessed at monthly intervals during the first 6 months and
Publicado em: 2003
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4. Protection against Plasmodium chabaudi Malaria Induced by Immunization with Apical Membrane Antigen 1 and Merozoite Surface Protein 1 in the Absence of Gamma Interferon or Interleukin-4
Strategies to optimize formulations of multisubunit malaria vaccines require a basic knowledge of underlying protective immune mechanisms induced by each vaccine component. In the present study, we evaluated the contribution of antibody-mediated and cell-mediated immune mechanisms to the protection induced by immunization with two blood-stage malaria vaccine
American Society for Microbiology.
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5. Differential Biological and Adjuvant Activities of Cholera Toxin and Escherichia coli Heat-Labile Enterotoxin Hybrids
Two bacterial products that have been demonstrated to function as mucosal adjuvants are cholera toxin (CT), produced by various strains of Vibrio cholerae, and the heat-labile enterotoxin (LT) produced by some enterotoxigenic strains of Escherichia coli. Although LT and CT have many features in common, they are clearly distinct molecules with biochemical and
American Society for Microbiology.