Animal Toxins
Mostrando 1-12 de 107 artigos, teses e dissertações.
-
1. BjussuLAAO-II induces cytotoxicity and alters DNA methylation of cell-cycle genes in monocultured/co-cultured HepG2 cells
Abstract Background: The use of animal venoms and their toxins as material sources for biotechnological applications has received much attention from the pharmaceutical industry. L-amino acid oxidases from snake venoms (SV-LAAOs) have demonstrated innumerous biological effects and pharmacological potential against different cancer types. Hepatocellular carc
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 11/03/2019
-
2. Deep sequencing analysis of toad Rhinella schneideri skin glands and partial biochemical characterization of its cutaneous secretion
Abstract Background: Animal poisons and venoms are sources of biomolecules naturally selected. Rhinella schneideri toads are widespread in the whole Brazilian territory and they have poison glands and mucous gland. Recently, protein from toads’ secretion has gaining attention. Frog skin is widely known to present great number of host defense peptides and
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 17/12/2018
-
3. Anti-ophidian activity of Bredemeyera floribunda Willd. (Polygalaceae) root extract on the local effects induced by Bothrops jararacussu venom
Bredemeyera floribunda roots are popularly used to treat snakebites in the semiarid region of Northeast Brazil, and previous studies indicate the anti-ophidian actions of triterpenoid saponins found in its roots. To assess B. floribunda root extract (BFRE) activity against the effects of Bothrops jararacussu venom (BjuV), antiphospholipasic, antiproteolytic,
Braz J Med Biol Res. Publicado em: 03/12/2018
-
4. Actiflagelin, a new sperm activator isolated from Walterinnesia aegyptia venom using phenotypic screening
Abstract Background Sperm contains a wealth of cell surface receptors and ion channels that are required for most of its basic functions such as motility and acrosome reaction. Conversely, animal venoms are enriched in bioactive compounds that primarily target those ion channels and cell surface receptors. We hypothesized, therefore, that animal venoms shou
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 22/02/2018
-
5. Differentiation of Toxic and Non-Toxic Leaves of Jatropha curcas L. Genotypes by Leaf Spray Mass Spectrometry
Jatropha curcas L. is an oil crop that has been studied as a potential source of biodiesel. A high protein pie is produced as a byproduct of the biodiesel production, which could be used as animal feed. However, the pie has toxic compounds, as phorbol esters and other toxins, which prevents the use as animal feed. For this reason, Embrapa (Brazilian Agricult
J. Braz. Chem. Soc.. Publicado em: 2017-08
-
6. Alpha-type phospholipase A2 inhibitors from snake blood
Abstract It is of popular and scientific knowledge that toxins from snake venom (among them the PLA2 and myotoxins) are neutralized by various compounds, such as antibodies and proteins purified from animal blood. Venomous and nonvenomous snakes have PLA2 inhibitory proteins, called PLIs, in their blood serum. One hypothesis that could explain the presence o
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 27/04/2017
-
7. Envenoming by Viridovipera stejnegeri snake: a patient with liver cirrhosis presenting disruption of hemostatic balance
Abstract Background In most cases of envenoming by the green habu Viridovipera stejnegeri in Taiwan coagulopathy is not observed. Case presentation Herein, we describe the case of a patient with liver cirrhosis who developed venom-induced consumptive coagulopathy after V. stejnegeri bite. Laboratory investigation revealed the following: prothrombin time
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 16/03/2017
-
8. Cytotoxic activity of Androctonus australis hector venom and its toxic fractions on human lung cancer cell line
Abstract Background: Several studies have showed that animal venoms are a source of bioactive compounds that may inhibit the growth of cancer cells, which makes them useful agents for therapeutic applications. Recently, it was established that venom toxins from scorpions induced cytotoxic, antiproliferative and apoptogenic effects on cancer cells. Therefore
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 01/12/2016
-
9. Arthropod venom Hyaluronidases: biochemical properties and potential applications in medicine and biotechnology
AbstractHyaluronidases are enzymes that mainly degrade hyaluronan, the major glycosaminoglycan of the interstitial matrix. They are involved in several pathological and physiological activities including fertilization, wound healing, embryogenesis, angiogenesis, diffusion of toxins and drugs, metastasis, pneumonia, sepsis, bacteremia, meningitis, inflammatio
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 10/11/2015
-
10. New insights into the structural characteristics of irradiated crotamine
Abstract Background: Since ionizing radiation has the potential to alter the molecular structure and affect the biologica properties of biomolecules, it has been successfully employed to attenuate animal toxins. The present study aimed to characterize the structural modifications on irradiated crotamine, a toxin from
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 11/08/2015
-
11. Clonal profile, virulence and resistance of Staphylococcus aureus isolated from sheep milk
The objective of this study was to characterize the clonal profile, virulence factors and antimicrobial resistance, particularly oxacillin resistance, of Staphylococcus aureus isolated from sheep milk. Milk samples were collected from all teats for the California Mastitis Test (CMT), somatic cell count, identification of S. aureus, investigation in these str
Braz. J. Microbiol.. Publicado em: 2015-06
-
12. Thalassophryne nattereri fish venom: from the envenoming to the understanding of the immune system
Thalassophryne nattereri (niquim) is a venomous fish found off North and Northeast coast of Brazil, where it is known by the severity of the accidents involving humans. This review article is divided into four topics. The first one provides a brief description of the animal biology and its distribution off Brazilian coastal waters, the venom apparatus, signs
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 02/09/2014