Annotation
Mostrando 1-12 de 744 artigos, teses e dissertações.
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1. Management strategies for implementing a multicenter cross-sectional study: lessons from the ADHERE Brazil study
ABSTRACT BACKGROUND: Epidemiological studies involving large samples usually face financial and operational challenges. OBJECTIVES: To describe the planning and execution of ADHERE Brazil, an epidemiological study on 1,105 kidney transplant patients, and report on how the study was structured, difficulties faced and solutions found. DESIGN AND SETTING: Cr
Sao Paulo Medical Journal. Publicado em: 2022
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2. Urethral reconstruction and genitoplasty highlighted in International Brazilian Journal of Urology
ABSTRACT Objective: Interstitial cystitis (IC)/bladder pain syndrome (BPS) is a chronic inflammatory disease that can cause bladder pain and accompanying symptoms, such as long-term urinary frequency and urgency. IC/BPS can be ulcerative or non-ulcerative. The aim of this study was to explore the core genes involved in the pathogenesis of ulcerative IC, and
Int. braz j urol.. Publicado em: 2021-08
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3. Exploration of the core genes in ulcerative interstitial cystitis/bladder pain syndrome
ABSTRACT Objective: Interstitial cystitis (IC)/bladder pain syndrome (BPS) is a chronic inflammatory disease that can cause bladder pain and accompanying symptoms, such as long-term urinary frequency and urgency. IC/BPS can be ulcerative or non-ulcerative. The aim of this study was to explore the core genes involved in the pathogenesis of ulcerative IC, and
Int. braz j urol.. Publicado em: 2021-08
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4. A Systematic Pipeline to Enhance the Fecal Metabolome Coverage by LC-HRMS
The comprehended knowledge of the metabolic profile of the fecal matter has been recognized as an important point for understanding metabolic changes in the human systemic metabolism and it can provide precious information about host-gut microbiota interactions. However, few analytical strategies have been addressed for a broad analysis of metabolites with d
J. Braz. Chem. Soc.. Publicado em: 2021-07
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5. Determining the pathogenicity of CFTR missense variants: Multiple comparisons of in silico predictors and variant annotation databases
Abstract Pathogenic variants in the Cystic Fibrosis Transmembrane Conductance Regulator gene (CFTR) are responsible for cystic fibrosis (CF), the commonest monogenic autosomal recessive disease, and CFTR-related disorders in infants and youth. Diagnosis of such diseases relies on clinical, functional, and molecular studies. To date, over 2,000 variants have
Genet. Mol. Biol.. Publicado em: 14/11/2019
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6. Identification of the molecular mechanisms associated with acute type A aortic dissection through bioinformatics methods
Aortic dissection is characterized by the redirection of blood flow, which flows through an intimal tear into the aortic media. The purpose of this study was to find potential acute type A aortic dissection (AAAD)-related genes and molecular mechanisms by bioinformatics. The gene expression profiles of GSE52093 were obtained from Gene Expression Omnibus (GEO
Braz J Med Biol Res. Publicado em: 07/11/2019
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7. AMÉRICA LATINA E ABYA YALA NO ENSINO DE HISTÓRIA ESPANHOL: O “DESCOBRIMENTO”, A CONQUISTA E AS CONTROVÉRSIAS DA LEYENDA NEGRA
RESUMO O trabalho explicita as representações contemporâneas da História da América no ensino de História na Espanha. Explicita e problematiza as configurações textuais e iconográficas que pretendem ensinar uma história do “descobrimento”, da conquista e da colonização da América. Usou-se a metodologia da pesquisa bibliográfica e de campo,
Hist. Educ.. Publicado em: 26/09/2019
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8. [PROVISIONAL] Genome sequence of Shewanella corallii strain A687 isolated from pufferfish (Sphoeroides spengleri)
Abstract We present here the genome sequence of Shewanella corallii strain A687 isolated from pufferfish Sphoeroides spengleri (Family Tetraodontidae). The assembly consists of 5,215,037 bp and contains 284 contigs, with a G+C content of 50.3%. The genus Shewanella comprises 67 recognized species. These bacteria are Gram-negative, rod-shaped, facultatively a
Genet. Mol. Biol.. Publicado em: 02/09/2019
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9. Searching for mutations in the HNF1B gene in a Brazilian cohort with renal cysts and hyperglycemia
ABSTRACT Objective To verify the presence of variants in HNF1B in a sample of the Brazilian population selected according to the presence of renal cysts associated with hyperglycemia. Subjects and methods We evaluated 28 unrelated patients with clinical suspicion of HNF1B mutation because of the concomitant presence of diabetes mellitus (DM) or prediabet
Arch. Endocrinol. Metab.. Publicado em: 02/05/2019
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10. Modelagem de processos de negócio: efeito do método de notação no nível de ambiguidade
Resumo A proposta deste estudo experimental controlado e aleatorizado foi analisar a especificação de requisitos funcionais. Avaliaram-se os possíveis impactos do método de notação de modelagem de processo no nível de ambiguidade presente na especificação em linguagem natural. As notações foram utilizadas como instrumento para manifestar as nece
Gest. Prod.. Publicado em: 18/03/2019
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11. A re-annotation of the Anopheles darlingi mobilome
Abstract The mobilome, portion of the genome composed of transposable elements (TEs), of Anopheles darlingi was described together with the genome of this species. Here, this mobilome was revised using similarity and de novo search approaches. A total of 5.6% of the A. darlingi genome is derived of TEs. Class I gypsy and copia were the most abundant superfam
Genet. Mol. Biol.. Publicado em: 21/01/2019
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12. Deep sequencing analysis of toad Rhinella schneideri skin glands and partial biochemical characterization of its cutaneous secretion
Abstract Background: Animal poisons and venoms are sources of biomolecules naturally selected. Rhinella schneideri toads are widespread in the whole Brazilian territory and they have poison glands and mucous gland. Recently, protein from toads’ secretion has gaining attention. Frog skin is widely known to present great number of host defense peptides and
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 17/12/2018