Anti Allergic Activity
Mostrando 1-12 de 39 artigos, teses e dissertações.
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1. Effect of Lavandula dentata extract on Ovalbumin-induced Asthma in Male Guinea Pigs
Resumo A asma é uma doença inflamatória dos pulmões e causa estresse oxidativo. Lavandula dentata é uma erva aromática com atividades anti-oxidantes e antiinflamatórias. Este estudo examinou a atividade do extrato de L. dentata em um modelo de asma de cobaia. Os machos adultos foram divididos em cinco grupos: o primeiro grupo foi controle, o segundo
Braz. J. Biol.. Publicado em: 18/04/2019
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2. Cloning, structural modelling and characterization of VesT2s, a wasp venom hyaluronidase (HAase) from Vespa tropica
Abstract Background: Wasp venom is a complex mixture containing proteins, enzymes and small molecules, including some of the most dangerous allergens. The greater banded wasp (Vespa tropica) is well-known for its lethal venom, whose one of the major components is a hyaluronidase (HAase). It is believed that the high protein proportion and activity of this e
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 01/12/2016
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3. Evaluation of anti-allergic and anti-anaphylactic activity of ethanolic extract of Zizyphus jujuba fruits in rodents
The present study reports the anti-allergic activity of ethanolic extract of Zizyphus jujubaMill., Rhamnaceae, and its possible mode of action. The effect of extract of Z. jujuba at different doses (250, 500 and 1000 mg/kg, orally) was simulated on studied animal models of asthma and allergy: a) milk induced eosinophilia and leukocytosis; b) compound 48/80 i
Rev. bras. farmacogn.. Publicado em: 2013-10
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4. The skin tissue is adversely affected by TNF-alpha blockers in patients with chronic inflammatory arthritis: a 5-year prospective analysis
OBJECTIVE: We evaluated the incidence of and the main risk factors associated with cutaneous adverse events in patients with chronic inflammatory arthritis following anti-TNF-α therapy. METHODS: A total of 257 patients with active arthritis who were taking TNF-α blockers, including 158 patients with rheumatoid arthritis, 87 with ankylosing spondylitis a
Clinics. Publicado em: 2013-09
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5. Chalcones from Myracrodruon urundeuva are efficacious in guinea pig ovalbumin-induced allergic conjunctivitis
The objective of the study was to verify the effects of dimeric chalcones (urundeuvines A, B, and C) from Myracrodruon urundeuva Allemão, Anacardiaceae (a Brazilian anti-inflammatory species), on an allergic conjunctivitis model. Male guinea-pigs were sensitized with two intraperitoneal injections of ovalbumin (10 μg dissolved in 0.5 mL saline and emulsifi
Revista Brasileira de Farmacognosia. Publicado em: 12/08/2011
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6. Caracterização, análise físico-química e estabilidade térmica do complexo de inclusão ciclodextrina-17-valerato de betametasona / Physicochemical characterization and thermal stability evaluation of betamethasone 17-valerate cyclodextrincomplex
Preparation of formulations containing the active ingredient betamethasone 17-valerate (VB) is widely defunded within pharmaceutical industry, once it concerns an anti-inflammatory drug and an option, in the treatment of conditions in which corticosteroids therapy is indicated. Often employed in topical treatment of eye, ear and nose allergic and inflammator
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/11/2010
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7. ESTUDO FOTOQUÍMICO DA AÇÃO ANTI-RADICALAR DE COMPOSTOS POLIFENÓLICOS EMPREGANDO ESPECTROFOTOMETRIA E HPLC-UV
The interest in antioxidants has increased considerably in recent years as molecules that reduce lipid peroxidation may minimize or inhibit the oxidative damage caused to DNA, proteins and carbohydrates. Flavonoids, a group of secondary metabolites widely distributed in the plant kingdom, have properties of anti-inflammatory, antibacterial, antiviral, anti-a
Publicado em: 2010
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8. Efeito da fisalina e, isolada da Physalis angulata, em modelos de dermatite de contato induzida por tpa e oxazolona em camundongos / The effects of physalin e, isolated from Physalis angulata, on tpa and oxazolone induced contact dermatitis in mice
The physalin E (PHY E), isolated from the aerial parts of Physalis angulata (Solanaceae), was assessed in models of contact dermatitis induced by 13-acetate-12-o-tetradecanoyl-phorbol (TPA) and oxazolone (OXA) in mice. The irritant contact dermatitis was induced by acute topical administration of TPA (2,5 mg/ear) and evaluated after 4h. The PHY E topically a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/12/2009
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9. Biological sensors based on immune response cells applied to the study of anti-allergic activity of natural compounds. / Utilização de sensores biológicos baseados em células de resposta imune no estudo da atividade antialérgica de substâncias naturais.
Anti-allergic activity of extracts and isolated compounds obtained from natural sources was investigated using the mast-cell based biosensor system. Mast cells release beta-hexosaminidase enzyme which is used as a marker of degranulation. Flavonoids (quercetin-Qc and rutin-Rt) and polyphenolic acids (caffeic acid-Cf and dimethoxy cinnamic acid-Dm) were used
Publicado em: 2009
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10. DEVELOPMENT AND VALIDATION OF METHODOLOGY FOR THE EVALUATION OF FLUTICASONE BY LIQUID CHROMATOGRAPHY AND CAPILLARY ELECTROPHORESIS / DESENVOLVIMENTO E VALIDAÇÃO DE METODOLOGIA PARA AVALIAÇÃO DE FLUTICASONA POR CROMATOGRAFIA LÍQUIDA E ELETROFORESE CAPILAR
Fluticasone propionate (FP) is a synthetic glucocorticoid with potent anti-inflammatory activity that has been effectively used for the treatment of seasonal and allergic perennial rhinitis, minimizing systemic activity. In the present study, the methods were developed and validaded for assessment of FP in pharmaceutical products. The analysis by reversed-ph
Publicado em: 2009
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11. Pharmacological study of anti-allergic activity of Syzygium cumini (L.) Skeels
Myrtaceae is a plant family widely used in folk medicine and Syzygium and Eugenia are among the most important genera. We investigated the anti-allergic properties of an aqueous leaf extract of Syzygium cumini (L.) Skeels (SC). HPLC analysis revealed that hydrolyzable tannins and flavonoids are the major components of the extract. Oral administration of SC (
Brazilian Journal of Medical and Biological Research. Publicado em: 2007-01
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12. Histamine H1-receptor antagonists with immunomodulating activities: potential use for modulating T helper type 1 (Th1)/Th2 cytokine imbalance and inflammatory responses in allergic diseases
Being a first-line treatment for hypersensitivity allergic disease, histamine H1-receptor antagonists possess anti-inflammatory activity in addition to being H1-receptor antagonists. While it is not purely a histamine-related condition, hypersensitivity allergic disease is associated with an increase in the number of T helper type 2 (Th2) cells and Th2 cytok
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