Anticitrulline
Mostrando 1-4 de 4 artigos, teses e dissertações.
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1. Evaluation clinical-laboratory of patients with rheumatoid arthritis: comparative analysis of anticitrullina the rheumatoid factor and antibodies / AvaliaÃÃo clÃnico-laboratorial de pacientes com artrite reumatÃide: anÃlise comparativa do fator reumatÃide e de anticorpos anticitrulina
Rheumatoid arthritis is an inflammatory, chronic and auto-immune disease that develops in degrees of articular destruction and extra-articular changes being able to lead to functional disability. Besides clinical assessment the diagnosis is based on the determination of the rheumatoid factor being this one also positive in healthy people as well as in other
Publicado em: 2005
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2. Proteomic analysis of secreted proteins in early rheumatoid arthritis: anti‐citrulline autoreactivity is associated with up regulation of proinflammatory cytokines
BMJ Group.
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3. Anti-Sa antibodies: prognostic and pathogenetic significance to rheumatoid arthritis
Anti-Sa antibodies are detected in the serum of 20–47% of patients with rheumatoid arthritis. These antibodies have a high degree of specificity for the disease, and appear to identify a subset of early rheumatoid arthritis patients destined to have aggressive and destructive disease. It has recently been confirmed that anti-Sa antibodies are directed to c
BioMed Central.
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4. Modifications of myelin basic protein in DM20 transgenic mice are similar to those in myelin basic protein from multiple sclerosis.
Transgenic mice containing different numbers of transgenes (2-70) of the myelin proteolipid protein DM20 were phenotypically normal up to 3 mo of age, after which the mice containing 70 copies of the transgene spontaneously demyelinated and died at 10-12 mo. Since we demonstrated that demyelination in multiple sclerosis involved specific chemical changes in