Antigen Presentation
Mostrando 1-12 de 681 artigos, teses e dissertações.
-
1. Samsum ant venom modulates the immune response and redox status at the acute toxic dose in vivo
Abstract Background: Ant venoms express surface molecules that participate in antigen presentation involving pro- and anti-inflammatory cytokines. This work aims to investigate the expression of MHC-II, CD80 and CD86 on the polymorphonuclear cells (PMNs) in rats injected with samsum ant venom (SAV). Methods: Rats were divided into three groups - control,
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 02/12/2019
-
2. In vitro generation of human monocyte-derived dendritic cells methodological aspects in a comprehensive review
Abstract: Dendritic cells (DCs) initiate and shape both innate and adaptive immune responses. They are specialized in antigen presentation to naive T cells, thereby orchestrating the T cell immune responses. Human peripheral blood and tissues contain several subsets of phenotypically and functionally distinct DCs, which promote interactions between the exter
An. Acad. Bras. Ciênc.. Publicado em: 28/11/2019
-
3. Ovarian Sertoli-Leydig Cell Tumors: Epidemiological, Clinical and Prognostic Factors
Resumo Objetivo Descrever uma série de casos de tumores de células de Sertoli-Leydig (TCSLs) ovarianos. Métodos Revisão retrospectiva de 12 casos de TCSL tratados no Hospital de Câncer de Barretos entre outubro de 2009 e agosto de 2017. Resultados A mediana de idade foi 31 anos (15-71 anos). Um total de 9 pacientes (75,0%) apresentaram sintomas: 8
Rev. Bras. Ginecol. Obstet.. Publicado em: 15/08/2019
-
4. Variability in the virulence of specific Mycobacterium tuberculosis clinical isolates alters the capacity of human dendritic cells to signal for T cells
BACKGROUND Once in the pulmonary alveoli, Mycobacterium tuberculosis (Mtb) enters into contact with alveolar macrophages and dendritic cells (DCs). DCs represent the link between the innate and adaptive immune system owing to their capacity to be both a sentinel and an orchestrator of the antigen-specific immune responses against Mtb. The effect that the v
Mem. Inst. Oswaldo Cruz. Publicado em: 12/08/2019
-
5. Dendritic cells and their relation to apical peridontitis
Abstract: The purpose of this manuscript was to re-discuss apical periodontitis, apical biofilm, and its possible relationship with dendritic cells (DC). DCs are potent regulators of the immune system and their function is divided into three categories that involve the presentation of antigens: the presentation of antigens and activation of T cells; a not we
Braz. oral res.. Publicado em: 18/10/2018
-
6. Pathology and pathogenesis of human leptospirosis: a commented review
ABSTRACT Leptospirosis is an acute bacterial septicemic febrile disease caused by pathogenic leptospires, which affect humans and animals in all parts of the world. Transmission can occur by direct contact with infected animals or, more commonly, through indirect contact with water or soil contaminated with urine from infected animals. Leptospires enter the
Rev. Inst. Med. trop. S. Paulo. Publicado em: 28/05/2018
-
7. Predicting pathway cross-talks in ankylosing spondylitis through investigating the interactions among pathways
Given that the pathogenesis of ankylosing spondylitis (AS) remains unclear, the aim of this study was to detect the potentially functional pathway cross-talk in AS to further reveal the pathogenesis of this disease. Using microarray profile of AS and biological pathways as study objects, Monte Carlo cross-validation method was used to identify the significan
Braz J Med Biol Res. Publicado em: 13/11/2017
-
8. Neurological complications and death in children with dengue virus infection: report of two cases
Abstract Background Dengue virus infection can have different complications; the best known is hemorrhagic dengue fever. However, other effects such as neurological disorders may endanger the lives of patients. Dengue neurological manifestations can be confused with encephalitis symptoms and can lead to cerebral edema and death. Therefore, we consider impor
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 06/07/2017
-
9. Subversion of immunoproteasome subunit expression in dengue virus serotype 2-infected HepG2 cells
Abstract: INTRODUCTION: Infection with all serotypes of dengue virus (DV) results in augmented antigen presentation by MHC class I molecules. However, the upregulation of immunoproteasome subunits only results from infection with two serotypes. This study aims to elucidate changes in the expression of immunoproteasome subunits resulting from infection with
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-02
-
10. Expression of co-stimulatory molecules CD80 and CD86 is altered in CD14 + HLA-DR + monocytes from patients with Chagas disease following induction by Trypanosoma cruzi recombinant antigens
Abstract INTRODUCTION The relationships between monocytes and lymphocytes through MHC class II molecules and costimulatory, are of utmost importance for the production of an efficient immune response. In this work, we assessed the expression of surface molecules CD80 and CD86 on CD14+HLA-DR+ monocytes from patients with Chagas disease. METHODS: The study
Rev. Soc. Bras. Med. Trop.. Publicado em: 2016-10
-
11. Human FcRn can mediate the transport across intestinal mucosal barrier and prolong the half-life of rabbit IgG in vivo
FcRn (neonatal Fc receptor) plays an important role in IgG transportation, antigen presentation and signal transmission. In this study, the complement fixation test and flow cytometry test were performed to verify whether the heterologous antibody could be transmitted to the serum or leukocyte with FcγR (Fc gamma receptor) across the intestinal mucosa. The
Braz. arch. biol. technol.. Publicado em: 2015-06
-
12. Differential expression of the costimulatory molecules CD86, CD28, CD152 and PD-1 correlates with the host-parasite outcome in leprosy
Leprosy is a spectral disease exhibiting two polar sides, namely, lepromatous leprosy (LL) characterised by impaired T-cell responses and tuberculoid leprosy in which T-cell responses are strong. Proper T-cell activation requires signalling through costimulatory molecules expressed by antigen presenting cells and their ligands on T-cells. We studied the infl
Mem. Inst. Oswaldo Cruz. Publicado em: 2012-12