5-Aminolevulinic acid synthesis in Escherichia coli requires expression of hemA.
AUTOR(ES)
Chen, W
RESUMO
hemA and hemM, which are 213 bp apart and divergently transcribed, were separately cloned. We found that hemA is required for 5-aminolevulinic acid (ALA) synthesis in two ALA- auxotrophs. Overexpression of hemM alone did not produce ALA. More ALA was produced by strains harboring a plasmid with both hemA and hemM than by those with hemA alone. We conclude that hemA alone is required for ALA synthesis but hemA and hemM are required for maximal ALA synthesis.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=205417Documentos Relacionados
- Expression of the Rhodobacter sphaeroides hemA and hemT genes, encoding two 5-aminolevulinic acid synthase isozymes.
- Regulation of the hemA gene during 5-aminolevulinic acid formation in Pseudomonas aeruginosa.
- 5-Aminolevulinic acid synthesis in Escherichia coli.
- 5-Aminolevulinic Acid Availability and Control of Spectral Complex Formation in HemA and HemT Mutants of Rhodobacter sphaeroides
- 5-Aminolevulinic acid availability and control of spectral complex formation in hemA and hemT mutants of Rhodobacter sphaeroides.
