A Drosophila ribosomal protein functions in mammalian cells.
AUTOR(ES)
Maki, C G
RESUMO
A cDNA expression vector encoding Drosophila ribosomal protein S14 was transfected into cultured Chinese hamster ovary (CHO) cells that harbor a recessive RPS14 emetine resistance mutation. Transformants synthesized the insect mRNA and polypeptide and consequently displayed an emetine-sensitive phenotype. These observations indicate that the insect protein was accurately expressed and correctly assembled into functional mammalian 40S ribosomal subunits.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=361039Documentos Relacionados
- A cloned human ribosomal protein gene functions in rodent cells.
- Role of ribosomal subunits in protein synthesis in mammalian cells.
- Functions of purified E1A protein microinjected into mammalian cells.
- A heptanucleotide sequence mediates ribosomal frameshifting in mammalian cells.
- DNA ligase I mediates essential functions in mammalian cells.
