A hungarian study on Werdnig-Hoffmann disease.
AUTOR(ES)
Czeizel, A
RESUMO
The prevalence of Werdnig-Hoffmann disease was found to be 0.66 per 10,000 livebirths in Hungary from 1973 to 1980. However, the true prevalence is estimated to be 1 per 10,000 livebirths, which exceeds the level of a previously published English study. There was no higher fetal death rate in previous and subsequent pregnancies of index patients' mothers. The occurrence in sibs was 32%, probably because of greater ascertainment in families with more than one affected child.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1015756Documentos Relacionados
- Large scale deletions of the 5q13 region are specific to Werdnig-Hoffmann disease.
- Prenatal prediction of Werdnig-Hoffmann disease using linked polymorphic DNA probes.
- Nephrogenic diabetes insipidus and Werdnig-Hoffmann disease in a child: an unusual association.
- The Gene Frequency of Acute Werdnig-Hoffmann Disease (SMA Type 1). A Total Population Survey in North-East England
- Anestesia venosa total (AVT) em lactente com doença de Werdnig-Hoffmann: relato de caso