A MECHANISM FOR GENETIC RECOMBINATION GENERATING ONE PARENT AND ONE RECOMBINANT*
AUTOR(ES)
Boon, Thierry
RESUMO
A mechanism is proposed for generating one parental and one recombinant genome in a single recombination event between two DNA molecules. Three stages of the event are described: initiation, replication, and return. Initiation requires breakage and joining of strands. Replication proceeds through a biparental “replication fork” generated in initiation. Return also involves breakage and joining of strands. Some of the implications of such a mechanism for genetic recombination are discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=223382Documentos Relacionados
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