A Murine Model of Renal Abscess Formation

AUTOR(ES)
FONTE

American Society for Microbiology

RESUMO

We developed a murine model of kidney abscess by direct renal injection of either Escherichia coli (1 × 106 to 7 × 106 organisms) or sterile medium. Bacterial infection produced renal abscesses, bacteremia, and late-onset leukocytosis in all animals. Controls were unaffected. This model may be useful for the study of various sequelae of kidney infection.

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