A New Relaxed Mutant of Escherichia coli with an Altered 50S Ribosomal Subunit
AUTOR(ES)
Friesen, J. D.
RESUMO
A new relaxed mutant called rel C has been isolated from a rel A+/rel A+ partial diploid strain. The rel C mutant is unable to synthesize ppGpp or pppGpp in vivo in response to amino acid starvation or in vitro, but can synthesize these nucleotides in a shift-down. Rel C maps near rif. Studies in vitro demonstrate the lesion to be probably in one of the 50S ribosomal proteins that can be removed by 1.0 M LiCl.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=433794Documentos Relacionados
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