A new strategy for mapping the human genome.

AUTOR(ES)

Shaw, D J

RESUMO

Recent advances in agarose gel electrophoresis of large DNA fragments raise the possibility of an entirely new approach to mapping mammalian genomes. In this article is discussed the potential of this technology for tackling problems such as construction of linkage maps, identifying chromosome translocation breakpoints, and moving from linked markers to genes causing diseases such as the muscular dystrophies and Huntington's chorea.

Documentos Relacionados

• Happy mapping: a proposal for linkage mapping the human genome.
• Coronavirus multiplication strategy. II. Mapping the avian infectious bronchitis virus intracellular RNA species to the genome.
• Physical mapping of the Mycoplasma pneumoniae genome.
• Transcription mapping of the varicella-zoster virus genome.
• Regional mapping of the phenylalanine hydroxylase gene and the phenylketonuria locus in the human genome.