A Proposed Hydrogen Transfer Function for Cytochrome c
AUTOR(ES)
Harrison, John E.
RESUMO
Outlines of proposed mechanisms for cytochrome c oxidoreduction are presented which differ in detail from those previously published. The mechanisms, while accommodating the fact that cytochrome c is a net electron acceptor and donor in its catalytic cycle, dictate that the enzyme catalyses hydrogen transfer. It is shown that the mechanism of cytochrome c reduction fulfills a recent proposal that the transition state is an analogue of the structure of ferricytochrome c2. The implications of a hydrogen transfer role of cytochrome c are discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=388447Documentos Relacionados
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