A strategy for oligonucleotide microarray probe reduction
AUTOR(ES)
Antipova, Alena A
FONTE
BioMed Central
RESUMO
One of the factors limiting the number of genes that can be analyzed on high-density oligonucleotide arrays is that each transcript is probed by multiple oligonucleotide probes. To reduce the number of probes required for each gene, a systematic approach to choosing the most representative probes is needed. A generalizable empiric method is presented for reducing the number of probes per gene while maximizing the fidelity to the original array design.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=151175Documentos Relacionados
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