Abnormal Mitochondrial Genomes in Yeast Restored to Respiratory Competence
AUTOR(ES)
Oakley, K. M.
RESUMO
When crosses are performed between newly arisen, spontaneous petite mutants of Saccharomyces cerevisiae, respiratory competent (restored) colonies can form. Some of the restored colonies are highly sectored and produce large numbers of petite mutants. The high-frequency petite formation trait is inherited in a non-Mendelian manner, and elimination of mitochondrial DNA from these strains results in the loss of the trait. These results indicate that abnormal mitochondrial genomes are sometimes formed during restoration of respiratory competence. It is hypothesized that these abnormalities result either from recombination between mitochondrial DNA fragments to produce molecules having partial duplications contained on inverted or transposed sequences, or else recombinational "hot spots" have been expanded.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1213904Documentos Relacionados
- Elevated Levels of Petite Formation in Strains of SACCHAROMYCES CEREVISIAE Restored to Respiratory Competence. II. Organization of Mitochondrial Genomes in Strains Having High and Moderate Frequencies of Petite Mutant Formation
- Elevated Levels of Petite Formation in Strains of SACCHAROMYCES CEREVISIAE Restored to Respiratory Competence. I. Association of Both High and Moderate Frequencies of Petite Mutant Formation with the Presence of Aberrant Mitochondrial DNA
- A comparison of three fission yeast mitochondrial genomes
- Prion-Dependent Switching between Respiratory Competence and Deficiency in the Yeast nam9-1 Mutant
- Recombination sequences in plant mitochondrial genomes: diversity and homologies to known mitochondrial genes.
