AcrD of Escherichia coli Is an Aminoglycoside Efflux Pump
AUTOR(ES)
Rosenberg, Emiko Y.
FONTE
American Society for Microbiology
RESUMO
AcrD, a transporter belonging to the resistance-nodulation-division family, was shown to participate in the efflux of aminoglycosides. Deletion of the acrD gene decreased the MICs of amikacin, gentamicin, neomycin, kanamycin, and tobramycin by a factor of two to eight, and ΔacrD cells accumulated higher levels of [3H]dihydrostreptomycin and [3H]gentamicin than did the parent strain.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=94475Documentos Relacionados
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