Activity of BMS-284756, a Novel Des-Fluoro(6) Quinolone, against Staphylococcus aureus, Including Contributions of Mutations to Quinolone Resistance

AUTOR(ES)

Low, D. E.

FONTE

American Society for Microbiology

RESUMO

The in vitro activity of BMS-284756 against 602 Staphylococcus aureus isolates, including 152 that were both methicillin and ciprofloxacin resistant (MIC ≥4 μg/ml), was determined. For ciprofloxacin-susceptible and nonsusceptible isolates, the MICs at which 50% of organisms were inhibited were 0.015 and 2 μg/ml and the MICs at which 90% of organisms were inhibited were 0.03 and 4 μg/ml, respectively.

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