Adrenal Corticosteroids Enhance Production of Type-C Virus Induced by 5-Iodo-2′-Deoxyuridine from Cultured Mouse Fibroblasts

AUTOR(ES)
RESUMO

Induction of RNA “tumor” viruses by 5-iodo-2′-deoxyuridine in mouse fibroblasts is stimulated 5- to 25-fold by glucogenic adrenal corticosteroids. Enhancement of virus production by the hormones is inhibited by low concentration of cordycepin, an inhibitor of poly(A) synthesis.

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