Alpha-Toxin Damages the Air-Blood Barrier of the Lung in a Rat Model of Staphylococcus aureus-Induced Pneumonia
AUTOR(ES)
McElroy, Mary C.
FONTE
American Society for Microbiology
RESUMO
We have shown that injury to alveolar epithelial type I cells may account, in part, for damage to the air-blood barrier of the lung in a rat model of Staphylococcus aureus pneumonia. We have also shown that alpha-toxin is an important cause of damage to the air-blood barrier; however, our data suggest that the toxin is not acting directly on alveolar type I cells.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=96922Documentos Relacionados
- Alpha-toxin of Staphylococcus aureus.
- Identification of a chromosomal determinant of alpha-toxin production in Staphylococcus aureus.
- Regulated Antisense RNA Eliminates Alpha-Toxin Virulence in Staphylococcus aureus Infection
- Thickness of the air-blood barriers in vertebrate lungs.
- Alpha-Toxin Is Required for Biofilm Formation by Staphylococcus aureus