An assessment of lung volumes and gas transfer in sickle-cell anaemia

AUTOR(ES)
RESUMO

Lung volumes, gas transfer, and anthropometry were assessed in sickle-cell anaemia in 13 patients with previous pulmonary episodes and 12 without this history. Respiratory symptoms were assessed with a standard questionnaire, total lung capacity and its subdivisions, the carbon monoxide transfer factor (TF), diffusion capacity of the alveolar capillary membrane (Dm), and the alveolar capillary blood volume (Vc) were measured, and stature, sitting height and chest diameters were recorded. Total lung capacity and vital capacity were reduced because the thorax was small relative to body size in these patients.

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