An RNA fraction in chromatin of L-929 cells associated with DNA
AUTOR(ES)
Monahan, John J.
RESUMO
The DNA of L-929 cell nuclei was examined for the presence of an RNA fraction hybridized to the DNA that could possibly serve a role in gene regulation. A low molecular weight ([unk]4.5S) RNA fraction was observed as an RNA-DNA complex in chromatin preparations subfractionated on a Cs2SO4 density gradient. This RNA does not appear to be covalently attached to the DNA. Neither does it appear to be attached to the DNA via a protein component. The RNA is resistant to ribonuclease H but is slowly attached by ribonuclease A + Tl. A role for, as well as the nature of the attachment of this RNA to DNA is suggested.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=343422Documentos Relacionados
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