Analysis of cell division in single clones of the Escherichia coli K-12 lexA mutant.
AUTOR(ES)
Howe, W E
RESUMO
The growth of clones of lexA mutant and lexA+ cells was analyzed. During normal growth lexA mutant clones frequently divided early, producing smaller newborn cells than the lexA+ clones. Some newborn cells in the lexA clones did not elongate or divide at all, a response that was never observed in the lexA+ clones. When starved for thymidine, most of the lexA mutant clones elongated and subsequently divided. The majority of lexA+ clones also elongated but did not divide. The above results suggest that one of the functions of the lexA+ gene is coordination of DNA repair with cell division.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=222162Documentos Relacionados
- Distribution of cell lengths in cultures of a lexA mutant of Escherichia coli K-12.
- The Escherichia coli K-12 lexA2 gene encodes a hypocleavable repressor.
- Identification of the lexA gene product of Escherichia coli K-12.
- Nucleotide sequence of the lexA gene of Escherichia coli K-12.
- Nucleotide sequencing of the ruv region of Escherichia coli K-12 reveals a LexA regulated operon encoding two genes.