Analysis of Moloney murine leukemia virus revertants mutated at the gag-pol junction.
AUTOR(ES)
Odawara, T
RESUMO
Among Moloney murine leukemia viruses (Mo-MuLVs) having stop codons other than UAG at the gag-pol junction, Mo-MuLV with UAA, but not with UGA, had a replication disadvantage. Mo-MuLV with a glutamine codon (CAG) at the junction did not replicate. A revertant of this virus consisted of the original virus and a virus with a deletion of the pol region. Protease and Pr65gag encoded by their respective genomes complemented each other.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=250367Documentos Relacionados
- Mutational analysis of the gag-pol junction of Moloney murine leukemia virus: requirements for expression of the gag-pol fusion protein.
- The effect of specific mutations at and around the gag-pol gene junction of Moloney murine leukaemia virus.
- Identification of amino acids inserted during suppression of UAA and UGA termination codons at the gag-pol junction of Moloney murine leukemia virus.
- Structure of glycosylated and unglycosylated gag and gag-pol precursor proteins of Moloney murine leukemia virus.
- Nucleotide sequence of the gag gene and gag-pol junction of feline leukemia virus.