Antibiotics for the empirical treatment of acute infectious diarrhea in children
AUTOR(ES)
Diniz-Santos, Daniel R., Silva, Luciana R., Silva, Nanci
FONTE
Brazilian Journal of Infectious Diseases
DATA DE PUBLICAÇÃO
2006-06
RESUMO
While the routine use of antibiotics for infectious diarrhea in children must be avoided, because it brings little benefit in most cases and is associated with the risk of increasing antimicrobial resistance, selected cases may require antimicrobial therapy, and the choice of the antimicrobial agent often has to be made empirically. Physicians prescribing antimicrobials in such a setting have not only to be aware of the most likely pathogens, but also of their characteristic antimicrobial susceptibility pattern and the safety profile of the various drugs. We reviewed the literature on the use of ampicillin, beta-lactamase inhibitors, trimethoprim-sulfamethoxazole, chloramphenicol, tetracyclines, nalidixic acid, fluoroquinolones, third-generation cephalosporins, macrolides, metronidazole and malabsorbed agents in the setting of acute infectious diarrhea, and we evaluated the available information, seeking to apply it to empirical use, highlighting clinically-useful pharmacological information and patients' and pathogens' characteristics that must be taken into account for decisions about antimicrobial therapy.
Documentos Relacionados
- Treatment of acute pyelonephritis in children: Evidence favours the oral route and a short course of appropriate antibiotics
- The effectiveness of a rotavirus vaccine in preventing hospitalizations and deaths presumably due to acute infectious diarrhea in Brazilian children: a quasi-experimental study
- Rare severe mycotic infections in children receiving empirical caspofungin treatment for febrile neutropenia
- New and future antibiotics in the treatment of acute respiratory tract infections.
- Treatment of Acute Infectious and Contagious Diseases