Anticardiolipin antibodies in patients with primary immunodeficiency diseases.
AUTOR(ES)
Pascual-Salcedo, D
RESUMO
The presence of antibodies to cardiolipin was determined (by an ELISA) in 143 patients with primary immunodeficiency diseases. Thirty (21%) had raised anticardiolipin antibody levels compared with only three in 98 age matched controls. The highest prevalence of this autoantibody was found in the Wiskott-Aldrich syndrome. Patients with selective IgA deficiency also showed a high prevalence of this autoantibody (32%), while patients with severe defects in antibody production showed a low prevalence or did not have such autoantibodies. This study provides further evidence of the association between autoimmune phenomena and primary immunodeficiency diseases.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1003535Documentos Relacionados
- Antibodies to HTLV-I in sera from patients with connective tissue diseases.
- Bronchoalveolar lavage cell analysis in patients with human immunodeficiency virus related diseases.
- Anticardiolipin antibodies in drug addicted patients with AIDS.
- Primary antiphospholipid syndrome: features of patients with raised anticardiolipin antibodies and no other disorder.
- Laparoscopic splenectomy in patients with hematologic diseases.