Anticoagulant antibodies in the synovial membranes of patients suffering from haemophilia, rheumatoid arthritis and other rheumatic disorders.
AUTOR(ES)
Rainsford, S G
RESUMO
This study has identified IgG and IgM anticoagulant antibodies in the synovial membranes of patients suffering from haemophilia and rheumatoid arthritis (RA) but not in synovial tissues from normal subjects or in patients with other arthritides. In the majority of cases the antibody appeared to have the specificity of the lupus-like anticoagulant (LLA) seen in patients with systemic lupus erythematosus (SLE). The importance of these findings with regard to the treatment of certain cases of haemophilia and RA and the possible relation between the presence of these antibodies and viral infections is discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=497748Documentos Relacionados
- Mycoplasma fermentans, but not M penetrans, detected by PCR assays in synovium from patients with rheumatoid arthritis and other rheumatic disorders.
- Immune interferon in serum and synovial fluid in rheumatoid arthritis and related disorders.
- Virus antibodies in serum and synovial fluid of patients with rheumatoid arthritis and other connective tissue diseases.
- Cytokine expression in synovial membranes of patients with rheumatoid arthritis and osteoarthritis.
- Characteristics of immunocompetent cells in synovial membranes from multiple sites in patients with rheumatoid arthritis.