Antifungal Therapy of Murine Aspergillus terreus Infection

AUTOR(ES)

Graybill, John R.

FONTE

American Society for Microbiology

RESUMO

Aspergillus terreus is a species which is being seen increasingly frequently and which is highly resistant to amphotericin B in vitro and clinically. We evaluated amphotericin B, caspofungin, and posaconazole in a murine model of acute invasive aspergillosis. Caspofungin and posaconazole both appeared beneficial and may be reasonable treatment alternatives for infection with A. terreus.

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