Antigenic variation within serotypes of Cryptococcus neoformans detected by monoclonal antibodies specific for the capsular polysaccharide.
AUTOR(ES)
Spiropulu, C
RESUMO
The serotype-specific polysaccharide was isolated from four to seven strains of each of the four major serotypes of Cryptococcus neoformans. Reactivities of polysaccharides with seven monoclonal antibodies raised against polysaccharides of serotypes A, B, C, and D were assessed by an enzyme-linked immunosorbent assay and double immunodiffusion. The results indicated that there is heterogeneity within all four serotypes in the expression of epitopes reactive with monoclonal antibodies.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=260798Documentos Relacionados
- Production and characterization of monoclonal antibodies specific for Cryptococcus neoformans capsular polysaccharide.
- Serotyping of Cryptococcus neoformans by using a monoclonal antibody specific for capsular polysaccharide.
- Opsonization of Cryptococcus neoformans by a family of isotype-switch variant antibodies specific for the capsular polysaccharide.
- Characterization of Cryptococcus neoformans capsular glucuronoxylomannan polysaccharide with monoclonal antibodies.
- Production, characterization, and antibody specificity of a mouse monoclonal antibody reactive with Cryptococcus neoformans capsular polysaccharide.