Antipneumococcal Activity of BMS 284756 Compared to Those of Six Other Agents

AUTOR(ES)
FONTE

American Society for Microbiology

RESUMO

Antipneumococcal activity of BMS 284756 was compared to those of six agents by MIC and time-kill methodologies. BMS 284756 had the lowest MICs compared to those of ciprofloxacin, levofloxacin, and moxifloxacin against quinolone-susceptible (≤0.016 to 0.06 μg/ml) and quinolone-resistant (0.03 to 1 μg/ml) pneumococci. BMS 284756 was bactericidal against 11 of 12 strains at two times the MIC after 24 h.

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