ATP-induced conformational changes in the restriction endonuclease from Escherichia coli K-12.
AUTOR(ES)
Bickle, T A
RESUMO
ATP induces a conformational change in the Escherichia coli K-12 restriction enzyme that allows it to discriminate between unmodified and modified DNA recognition sequences. This conformational change does not require ATP hydrolysis. However, ATP hydrolysis is a requirement for DNA cleavage.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=392721Documentos Relacionados
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