Autolysis in Staphylococcus aureus: Preferential Release of Old Cell Walls
AUTOR(ES)
Gilpin, R. W.
RESUMO
The kinetics of release of old versus new cell wall in two strains of Staphylococcus aureus were studied during autolysis. In both strains the autolytic enzyme is an amidase. Cells were double labeled with 3H and 14C, and the distribution of radioactivity in the cell walls was monitored during autolysis. In all cases the rate of release of steady-state lable from peptidoglycan was significantly higher than that of pulse label. Identical results were obtained with whole cells or isolated cell walls. The results suggest that in S. aureus the old cell wall is preferentially released during autolysis.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=245667Documentos Relacionados
- Mechanism of Autolysis of Isolated Cell Walls of Staphylococcus aureus1
- Autolysis-defective mutant of Staphylococcus aureus: pathological considerations, genetic mapping, and electron microscopic studies.
- The AbcA Transporter of Staphylococcus aureus Affects Cell Autolysis
- Regulation of Bacterial Cell Walls: Turnover of Cell Wall in Staphylococcus aureus
- Antimicrobial resistance of Staphylococcus aureus: genetic basis.