Avaliação histometrica da evolução da doenção periodontal experimental em ratos alimentados com uma dieta hiperlipidica / Histometric evaluation of the experimental periodontal disease in rats fed a hyperlipidic diet

AUTOR(ES)
DATA DE PUBLICAÇÃO

2007

RESUMO

The aim of this study was to evaluate, histometrically, the influence of a hyperlipidic diet on the evolution of experimental periodontal disease. Thirty-two male Wistar rats were randomly assigned to two groups: C (commercial chow diet) and H (hyperlipidic diet). Cotton ligatures were placed around the left first mandibular molar and the contralateral tooth was used as a control. The animals were sacrificed on days 7, 14, 21 and 28 days after ligature placement for evaluation of periodontal disease progression. The specimens were routinely processed for serial decalcified sections and histometric analysis was performed to evaluate bone loss in the furcation area with the help of an image analysis software, ImagePro®. In the moment of the sacrifice it was noticed a greater accumulation food debris on the teeth with ligature of both groups, it was also noticed a greater accumulation of adipose tissue in group H, due to the kind of diet that the animals were fed, which has an elevated concentration of lipids. The data was analyzed using the ANOVA and Tukey?s test at a significance level of 5%. Intergroup analysis did not show significant differences in relation to loss of bone volume for both the ligated and unligated teeth between time intervals (p>0.05). Intragroup analysis, however, showed a greater amount of bone volume loss in the ligated teeth than in the unligated ones (p<0.0001). I could be concluded that the consumption of a hyperlipidic diet does not influence bone loss in ligature-induced periodontal disease in rats.

ASSUNTO(S)

ratos wistar rats periodontite wistar bone resorption reabsorção ossea periodontitis

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