Base excision repair in the thermophile Thermus sp. strain X-1.
AUTOR(ES)
Warner, H R
RESUMO
The thermophile Thermus sp. strain X-1, grown at 70 degrees C, contains uracil-DNA glycosylase and apurinic endonuclease activities, both of which are known to have roles in the repair of DNA damaged by heat. Both of these activities have temperature optima of about 70 degrees C. However, neither of these activities is present in quantities significantly greater than that found in Escherichia coli grown at 37 degrees C. Therefore, it appears that thermophilic organisms may not contain greatly elevated levels of the enzymes thought to be involved in the repair of DNA damaged by heat.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=217623Documentos Relacionados
- Thermus aquaticus gen. n. and sp. n., a Nonsporulating Extreme Thermophile
- Functions of the Mismatch Repair Gene mutS from Acinetobacter sp. Strain ADP1†
- Base excision repair in sugarcane
- Purification and Characterization of the Recombinant Thermus sp. Strain T2 α-Galactosidase Expressed in Escherichia coli
- Protein turnover in the extreme thermophile Thermus aquaticus.