Biosynthesis of vitamin B12: mode of incorporation of factor III into cobyrinic acid.

AUTOR(ES)
RESUMO

Extensive chemical degradation of cobyrinic acid biosynthesized from a sample of factor III radiochemically labeled in its three methyl groups demonstrates that label is retained exclusively in the two methyl groups at positions C-2 and C-7 and confirms that the C-20 methyl group of the precursor is lost during formation of the corrin ring system.

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