Bleomycin, an Antitumor Antibiotic: Improved Microbiological Assay and Tissue Distribution Studies in Normal Mice
AUTOR(ES)
Pittillo, Robert F.
RESUMO
A microbiological assay was developed for bleomycin, an antitumor antibiotic reported to be active in human trials. The assay bacterium was a strain of Escherichia coli which is resistant to ethionine. Studies revealed relatively high concentrations of bleomycin in the blood and urine of mice after a single dose, < 0.33 ld10, injected intraperitoneally.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=376363Documentos Relacionados
- Chromomycin A3, an Antitumor Antibiotic: Tissue Distribution Studies in Mice as Measured by Microbial Assay
- Microbiological Assay and Tissue Distribution of 5-Diazouracil in Mice
- Thiopeptin, a New Feed Additive Antibiotic: Microbiological and Chemical Studies
- Microbiological Assay and Tissue Distribution of β-Thioguanine Deoxyriboside in Mice 1
- Pseudourea, 2,2′-(9,10-Anthrylenedimethylene) bis-(2-thio-, dihydrochloride) Dihydrate: Microbiological Assay and Tissue Distribution Studies in Mice1
