Bleomycin increases amikacin and streptomycin resistance in Escherichia coli harboring transposon Tn5.
AUTOR(ES)
Blazquez, J
RESUMO
The antitumor antibiotic bleomycin acts as a transcriptional inducer of the neo-ble-str operon of the transposon Tn5, increasing the resistance level to streptomycin and amikacin in Tn5-containing Escherichia coli. The mechanism may involve a recA-independent induction mediated by DNA damage.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=188104Documentos Relacionados
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