Blocking by Histones of Accessibility to DNA in Chromatin: Addition of Histones*
AUTOR(ES)
Mirsky, Alfred E.
RESUMO
The blocking effect of histones on accessibility of DNA to DNase has been studied by addition of various histones to chromatin in intact or histone-depleted thymus nuclei (those from which all lysine-rich histone was removed and those from which much of the arginine-rich histone was removed) and to deoxyribonucleoprotein (chromatin) extracted from nuclei. In each case lysine-rich histone, weight for weight, blocks accessibility more effectively than does arginine-rich histone. Fractions of the arginine-rich histone differ considerably from each other in their blocking efficacy. Phosphorylation of lysine-rich histone tempers its blocking effectiveness.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=389745Documentos Relacionados
- Blocking by histones of accessibility to DNA in chromatin: Addition of histones
- Blocking by Histones of Accessibility to DNA in Chromatin
- THE INTERACTION OF RNA POLYMERASE WITH HISTONES*
- Accessibility of DNA in Chromatin to DNA Polymerase and RNA Polymerase
- Left-handedly curved DNA regulates accessibility to cis-DNA elements in chromatin
