Botulism Due to Clostridium baratii Type F Toxin

AUTOR(ES)

Harvey, Sydney M.

FONTE

American Society for Microbiology

RESUMO

Botulism results from consumption of preformed toxin or in vivo toxin elaboration in wounds or intestine. Of U.S. food-borne botulism cases since 1950, the majority were due to toxin A, but a significant number of suspect cases were never confirmed by culture or toxin detection. We report here a possible case of food-borne botulism attributed to toxin F production by a Clostridium baratii organism isolated from food consumed by the patient. The isolation of a toxin-producing Clostridium species other than Clostridium botulinum from food and stool requires deviation from the usual laboratory protocols, which may account for the lack of complete laboratory confirmation of clinically diagnosed cases.

Documentos Relacionados

• Type F botulism due to neurotoxigenic Clostridium baratii from an unknown source in an adult.
• Monoclonal antibody to type F Clostridium botulinum toxin.
• Isolation of an organism resembling Clostridium barati which produces type F botulinal toxin from an infant with botulism.
• Genetic confirmation of identities of neurotoxigenic Clostridium baratii and Clostridium butyricum implicated as agents of infant botulism.
• Characterization of the neurotoxin isolated from a Clostridium baratii strain implicated in infant botulism.