Bullous pemphigoid and neurological disease: statistics from a dermatology service
AUTOR(ES)
Tarazona, Monica Jidid Mateus, Mota, Amanda Nascimento Cavalleiro de Macedo, Gripp, Alexandre Carlos, Unterstell, Natasha, Bressan, Aline Lopes
FONTE
An. Bras. Dermatol.
DATA DE PUBLICAÇÃO
2015-04
RESUMO
Bullous pemphigoid (BP) is an autoimmune, acquired, cutaneous disease caused by the production of autoantibodies against hemidesmosomes' components in the basement membrane. The estimated incidence in Europe ranges from 7 to 43 cases per million inhabitants per year. Several studies have reported an association between BP and neurological disorders (ND). Our cohort of Bullous pemphigoid and ND is the first in Brazil and showed a significantly high prevalence of neurological and/or psychiatric diseases, especially cerebrovascular accident (CVA) and dementia, in agreement with the prevalence reported in several studies published in the medical literature in recent years.
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