Cation Transport Alteration Associated with Plasmid-Determined Resistance to Cadmium in Staphylococcus aureus
AUTOR(ES)
Weiss, Alison A.
RESUMO
Plasmid-determined resistance to cadmium has only been found with plasmids from Staphylococcus aureus. Resistance to cadmium was associated with a lower accumulation of Cd2+ ions by the plasmid-bearing resistant cells. Cadmium accumulation by susceptible cells was energy dependent and had those characteristics usually associated with a transmembrane active transport system. There was a specific interrelationship between cadmium accumulation and manganese accumulation and retention. Cd2+ inhibited the uptake of Mn2+ and accelerated the loss of intracellular Mn2+ by the susceptible cells, but was without effect on Mn2+ transport in resistant S. aureus cells. Under similar conditions, there was no differential effect of Cd2+ on Mg2+, Zn2+, Co2+, Ni2+, or Rb+ accumulation or exchange between the susceptible and the resistant strains.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=352570Documentos Relacionados
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