CELL DIVISION IN A SPECIES OF ERWINIA IV. : Metabolic Blocks in Pantothenate Biosynthesis and their Relationship to Inhibition of Cell Division1

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Grula, Mary M. (Oklahoma State University, Stillwater) and E. A. Grula. Cell division in a species of Erwinia. IV. Metabolic blocks in pantothenate biosynthesis and their relationship to inhibition of cell division. J. Bacteriol. 83:989–997. 1962.—Four compounds that inhibit cell division in an Erwinia sp., d-serine, d-histidine, d-phenylalanine, and penicillin, decrease the intracellular pantothenate content of Erwinia at culture ages of 10 and 16 hr. In the case of penicillin, it appears to be the result of excessive leakage from long cells; however, with the three d-amino acids, there is a genuine inhibition of synthesis.

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