CELLS INVOLVED IN CELL-MEDIATED AND TRANSPLANTATION IMMUNITY, II. A CONSIDERATION OF THE FUNCTIONAL IDENTITY OF THE CELLS INVOLVED IN BOTH HUMORAL AND CELL-MEDIATED IMMUNITY: A PHYLOGENETIC APPROACH

AUTOR(ES)

Richter, Maxwell

RESUMO

The literature concerned with the types of cells that participate in the humoral and cell-mediated immune response has been reviewed. It is postulated that the initial cells that are involved in mediating both types of immunity are functionally identical in that both are antigen-reactive cells. In the case of the humoral immune response, the interaction of the antigen-reactive cells with the antigen leads to the release or transfer of “information” to the antibody-forming cell, resulting in the synthesis and secretion of antibody molecules. In the case of cell-mediated immunity, it is considered that the primitive antigen-reactive cell itself transforms into the sensitized cell which infiltrates the site of antigen administration.

Documentos Relacionados

• Respiratory Tract Cell-Mediated Immunity: Comparison of Primary and Secondary Response
• Candida mannan: chemistry, suppression of cell-mediated immunity, and possible mechanisms of action.
• Inflammatory Lymphocyte in Cell-Mediated Antibacterial Immunity: Factors Governing the Accumulation of Mediator T Cells in Peritoneal Exudates
• NK cell–mediated killing of target cells triggers robust antigen-specific T cell–mediated and humoral responses
• Cell-mediated and humoral immunity induced by a live Francisella tularensis vaccine.