Centromere-Linkage Analysis and Consolidation of the Zebrafish Genetic Map
AUTOR(ES)
Johnson, S. L.
RESUMO
The ease of isolating mutations in zebrafish will contribute to an understanding of a variety of processes common to all vertebrates. To facilitate genetic analysis of such mutations, we have identified DNA polymorphisms closely linked to each of the 25 centromeres of zebrafish, placed centromeres on the linkage map, increased the number of mapped PCR-based markers to 652, and consolidated the number of linkage groups to the number of chromosomes. This work makes possible centromere-linkage analysis, a novel, rapid method to assign mutations to a specific linkage group using half-tetrads.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1207124Documentos Relacionados
- Half-Tetrad Analysis in Zebrafish: Mapping the Ros Mutation and the Centromere of Linkage Group I
- Genetic Linkage Mapping of Zebrafish Genes and ESTs
- Centromere mapping and orientation of the molecular linkage map of rice (Oryza sativa L.).
- Genetic Linkage Map of the Edible Basidiomycete Pleurotus ostreatus
- A Genetic Linkage Map of the Male Goat Genome