Characterization of Murine Gammaherpesvirus 68 Glycoprotein B
AUTOR(ES)
Lopes, Filipa B.
FONTE
American Society for Microbiology
RESUMO
Murine gammaherpesvirus 68 (MHV-68) glycoprotein B (gB) was identified in purified virions by immunoblotting, immunoprecipitation, and immunoelectron microscopy. It was synthesized as a 120-kDa precursor in infected cells and cleaved into 65-kDa and 55-kDa disulfide-linked subunits close to the time of virion release. The N-linked glycans on the cleaved, virion gB remained partially endoglycosidase H sensitive. The processing of MHV-68 gB therefore appears similar to that of Kaposi's sarcoma-associated herpesvirus gB and human cytomegalovirus gB.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=525018Documentos Relacionados
- Characterization of murine gammaherpesvirus 68 glycoprotein B (gB) homolog: similarity to Epstein-Barr virus gB (gp110).
- Identification and characterization of murine gammaherpesvirus 68 gp150: a virion membrane glycoprotein.
- B Cells Regulate Murine Gammaherpesvirus 68 Latency
- Selective Gene Expression of Latent Murine Gammaherpesvirus 68 in B Lymphocytes
- Transcription Program of Murine Gammaherpesvirus 68