Characterization of the Earliest Known Staphylococcus aureus Plasmid Encoding a Multidrug Efflux System

AUTOR(ES)

Paulsen, Ian T.

FONTE

American Society for Microbiology

RESUMO

The staphylococcal qacB-encoding multidrug resistance plasmid pSK156, isolated from a clinical strain dating from 1951, was characterized. Comparison of the regions flanking qacB with other qacA- and qacB-encoding plasmids provided insights into the evolution and dissemination of these multidrug efflux genes and led to the detection of the earliest known copy of the insertion sequence IS257.

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