Chemical leukoderma induced by dimethyl sulfate
AUTOR(ES)
Gozali, Maya Valeska, Zhang, Jia-an, Yi, Fei, Zhou, Bing-rong, Luo, Dan
FONTE
An. Bras. Dermatol.
DATA DE PUBLICAÇÃO
2016-10
RESUMO
Abstract Chemical leukoderma occurs due to the toxic effect of a variety of chemical agents. Mechanisms include either destruction or inhibition of melanocytes. We report two male patients (36 and 51 years old) who presented with multiple hypopigmented macules and patches on the neck, wrist, and legs after exposure to dimethyl sulfate in a chemical industry. Physical examination revealed irregular depigmentation macules with sharp edges and clear hyperpigmentation around the lesions. History of repeated exposure to a chemical agent can help the clinical diagnosis of chemical leukoderma. This diagnosis is very important for prognosis and therapeutic management of the disease.
Documentos Relacionados
- Reaction of nucleosome DNA with dimethyl sulfate.
- CONJUNCTIVITIS DUE TO EXPOSURE TO DIMETHYL-SULFATE*
- Anaerobic degradation of methylmercaptan and dimethyl sulfide by newly isolated thermophilic sulfate-reducing bacteria.
- DNA fragments in Friend erythroleukemia cells induced by dimethyl sulfoxide.
- Conformation of yeast 18S rRNA. Direct chemical probing of the 5' domain in ribosomal subunits and in deproteinized RNA by reverse transcriptase mapping of dimethyl sulfate-accessible.
